Description：

SB431542 is a potent and selective inhibitor of ALK5 with IC50 of 94 nM in a cell-free assay, 100-fold more selective for ALK5 than p38 MAPK and other kinases.

Chemical Information：

Molecular Weight (MW)		384.39
Formula		C22H16N4O3
CAS No.		301836-41-9
Solubility (25°C) *	DMSO	76 mg/mL (197.71 mM)
	Water	Insoluble
	Alcohol	3 mg/mL (7.8 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6015 mL	13.0076 mL	26.0152 mL
5 mM	0.5203 mL	2.6015 mL	5.2030 mL
10 mM	0.2602 mL	1.3008 mL	2.6015 mL
50 mM	0.0520 mL	0.2602 mL	0.5203 mL

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