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S- (+)-Rolipram

S- (+)-Rolipram

Catalog Number: CC2283 Rank: comment rank 5

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Description:

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

Chemical Information:

Molecular Weight (MW) 275.34
Formula

 

C16H21NO3

 

CAS No. 85416-73-5
Solubility (25°C) * DMSO 55 mg/mL (199.75 mM)
Water Insoluble
Alcohol 55 mg/mL (199.75 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.6319 mL 18.1594 mL 36.3187 mL
5 mM 0.7264 mL 3.6319 mL 7.2637 mL
10 mM 0.3632 mL 1.8159 mL 3.6319 mL
50 mM 0.0726 mL 0.3632 mL 0.7264 mL


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