Description：

RXDX-106 (CEP-40783) is an orally-available, potent and selective TAM(TYRO3, AXL, MER)/MET inhibitor displaying low nanomolar biochemical activity and slow (T1/2 >120 min) inhibitor off-rate in peptide phosphorylation assays and in vitro kinase binding assays, respectively.

Chemical Information：

Molecular Weight (MW)		588.56
Formula		C31H26F2N4O6
CAS No.		1437321-24-8
Solubility (25°C) *	DMSO	10 mg/mL (16.99 mM)
	Water	Insoluble
	Alcohol	2 mg/mL (3.39 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6991 mL	8.4953 mL	16.9906 mL
5 mM	0.3398 mL	1.6991 mL	3.3981 mL
10 mM	0.1699 mL	0.8495 mL	1.6991 mL
50 mM	0.0340 mL	0.1699 mL	0.3398 mL

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