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Rosiglitazone

Rosiglitazone

Catalog Number: CC2712 Rank: comment rank 5

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Description:

Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively. Rosiglitazone is a pure ligand of PPAR-gamma, and has no PPAR-alpha-binding action.

Chemical Information:

Molecular Weight (MW) 357.43
Formula

 

C18H19N3O3S

 

CAS No. 122320-73-4
Solubility (25°C) * DMSO 71 mg/mL (198.64 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.7978 mL 13.9888 mL 27.9775 mL
5 mM 0.5596 mL 2.7978 mL 5.5955 mL
10 mM 0.2798 mL 1.3989 mL 2.7978 mL
50 mM 0.0560 mL 0.2798 mL 0.5596 mL


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