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RO4929097

RO4929097

Catalog Number: CC1731 Rank: comment rank 5

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$ 679.00
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Description:

RO4929097 is a γ secretase inhibitor with IC50 of 4 nM in a cell-free assay, inhibiting cellular processing of Aβ40 and Notch with EC50 of 14 nM and 5 nM, respectively. Phase 2.

Chemical Information:

Molecular Weight (MW) 469.4
Formula

 

C22H20F5N3O3

 

CAS No. 847925-91-1
Solubility (25°C) * DMSO 93 mg/mL (198.12 mM)
Water Insoluble
Alcohol 16 mg/mL (34.08 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1304 mL 10.6519 mL 21.3038 mL
5 mM 0.4261 mL 2.1304 mL 4.2608 mL
10 mM 0.2130 mL 1.0652 mL 2.1304 mL
50 mM 0.0426 mL 0.2130 mL 0.4261 mL


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