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Ripasudil (K-115) hydrochloride dihydrate

Ripasudil (K-115) hydrochloride dihydrate

Catalog Number: CC8151 Rank: comment rank 5

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$ 137.00
$ 487.00
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Description:

Ripasudil (K-115) hydrochloride dihydrate is potent ROCK inhibitor with IC50 of 51 nM and 19 nM for ROCK1 and ROCK2, respectively, used for the treatment of glaucoma and ocular hypertension.

Chemical Information:

Molecular Weight (MW) 395.88
Formula

 

C15H18FN3O2S.Cl H.2 H2 O

 

CAS No. 887375-67-9
Solubility (25°C) * DMSO 26 mg/mL warmed (65.67 mM)
Water 79 mg/mL (199.55 mM)
Alcohol 5 mg/mL warmed (12.63 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5260 mL 12.6301 mL 25.2602 mL
5 mM 0.5052 mL 2.5260 mL 5.0520 mL
10 mM 0.2526 mL 1.2630 mL 2.5260 mL
50 mM 0.0505 mL 0.2526 mL 0.5052 mL


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