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R788 (Fostamatinib) Disodium

R788 (Fostamatinib) Disodium

Catalog Number: CC2362 Rank: comment rank 5

Size Price Qty
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$ 679.00
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Description:

R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3.

Chemical Information:

Molecular Weight (MW) 624.42
Formula

 

C23H24FN6O9P.2Na

 

CAS No. 1025687-58-4
Solubility (25°C) * DMSO 6 mg/mL warmed (9.6 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.6015 mL 8.0074 mL 16.0149 mL
5 mM 0.3203 mL 1.6015 mL 3.2030 mL
10 mM 0.1601 mL 0.8007 mL 1.6015 mL
50 mM 0.0320 mL 0.1601 mL 0.3203 mL


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