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R406 (free base)

R406 (free base)

Catalog Number: CC1689 Rank: comment rank 5

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Description:

R406 (free base) is a potent Syk inhibitor with IC50 of 41 nM in a cell-free assay, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 1.

Chemical Information:

Molecular Weight (MW) 470.45
Formula

 

C22H23FN6O5

 

CAS No. 841290-80-0
Solubility (25°C) * DMSO 21 mg/mL (44.63 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.1256 mL 10.6281 mL 21.2562 mL
5 mM 0.4251 mL 2.1256 mL 4.2512 mL
10 mM 0.2126 mL 1.0628 mL 2.1256 mL
50 mM 0.0425 mL 0.2126 mL 0.4251 mL


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