Description：

Quizartinib (AC220) is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 nM/4.2 nM in MV4-11 and RS4;11 cells, respectively, 10-fold more selective for Flt3 than KIT, PDGFRα, PDGFRβ, RET, and CSF-1R. Phase 3.

Chemical Information：

Molecular Weight (MW)		560.67
Formula		C29H32N6O4S
CAS No.		950769-58-1
Solubility (25°C) *	DMSO	33 mg/mL (58.85 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7836 mL	8.9179 mL	17.8358 mL
5 mM	0.3567 mL	1.7836 mL	3.5672 mL
10 mM	0.1784 mL	0.8918 mL	1.7836 mL
50 mM	0.0357 mL	0.1784 mL	0.3567 mL

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