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Atglistatin

Atglistatin

Catalog Number: CC7520 Rank: comment rank 5

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Description:

Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases.

Chemical Information:

Molecular Weight (MW) 283.37
Formula

 

C17H21N3O

 

CAS No. 1469924-27-3
Solubility (25°C) * DMSO 56 mg/mL (197.62 mM)
Water Insoluble
Alcohol 4 mg/mL (14.11 mM)


Biological Activity:

Targets
IC50
FGFR-2 VEGFR2 c-Kit PDGFRα
170 nM 0.9 nM 40 nM 67 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.5290 mL 17.6448 mL 35.2896 mL
5 mM 0.7058 mL 3.5290 mL 7.0579 mL
10 mM 0.3529 mL 1.7645 mL 3.5290 mL
50 mM 0.0706 mL 0.3529 mL 0.7058 mL


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