Description：

QNZ (EVP4593) shows potent inhibitory activity toward both NF-κB activation and TNF-α production with IC50 of 11 nM and 7 nM in Jurkat T cells, respectively.

Chemical Information：

Molecular Weight (MW)		356.42
Formula		C22H20N4O
CAS No.		545380-34-5
Solubility (25°C) *	DMSO	5 mg/mL warmed (14.02 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.8057 mL	14.0284 mL	28.0568 mL
5 mM	0.5611 mL	2.8057 mL	5.6114 mL
10 mM	0.2806 mL	1.4028 mL	2.8057 mL
50 mM	0.0561 mL	0.2806 mL	0.5611 mL

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