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Prexasertib (LY2606368)

Prexasertib (LY2606368)

Catalog Number: CC7334 Rank: comment rank 5

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Description:

Prexasertib (LY2606368) is an ATP-competitive CHK1 inhibitor with a Ki value of 0.9 nmol/L. For CHK2 and RSK, its IC50 values are 8 nM and 9 nM respectively in cell-free assay.

Chemical Information:

Molecular Weight (MW) 438.31
Formula

 

C18H19N7O2.2ClH

 

CAS No. 1234015-54-3
Solubility (25°C) * DMSO 2 mg/mL (4.56 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.2815 mL 11.4075 mL 22.8149 mL
5 mM 0.4563 mL 2.2815 mL 4.5630 mL
10 mM 0.2281 mL 1.1407 mL 2.2815 mL
50 mM 0.0456 mL 0.2281 mL 0.4563 mL


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