Description：

PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.

Chemical Information：

Molecular Weight (MW)		512.53
Formula		C24H22F2N6O3S
CAS No.		1393465-84-3
Solubility (25°C) *	DMSO	100 mg/mL (195.11 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9511 mL	9.7555 mL	19.5111 mL
5 mM	0.3902 mL	1.9511 mL	3.9022 mL
10 mM	0.1951 mL	0.9756 mL	1.9511 mL
50 mM	0.0390 mL	0.1951 mL	0.3902 mL

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