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AT101

AT101

Catalog Number: CC2968 Rank: comment rank 5

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$ 102.00
$ 329.00
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Description:

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 μM, 0.48 μM and 0.18 μM in cell-free assays; does not inhibit BIR3 domain and BID. Phase 2.

Chemical Information:

Molecular Weight (MW) 578.61
Formula

 

C30H30O8.C2H4O2

 

CAS No. 866541-93-7
Solubility (25°C) * DMSO 116 mg/mL (200.48 mM)
Water Insoluble
Alcohol 89 mg/mL (153.81 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.7283 mL 8.6414 mL 17.2828 mL
5 mM 0.3457 mL 1.7283 mL 3.4566 mL
10 mM 0.1728 mL 0.8641 mL 1.7283 mL
50 mM 0.0346 mL 0.1728 mL 0.3457 mL


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