Description：

Pimasertib (AS-703026) is a highly selective, potent, ATP non-competitive allosteric inhibitor of MEK1/2 with IC50 of 5 nM-2 μM in MM cell lines. Phase 2.

Chemical Information：

Molecular Weight (MW)		431.20
Formula		C15H15FIN3O3
CAS No.		1236699-92-5
Solubility (25°C) *	DMSO	86 mg/mL (199.44 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3191 mL	11.5955 mL	23.1911 mL
5 mM	0.4638 mL	2.3191 mL	4.6382 mL
10 mM	0.2319 mL	1.1596 mL	2.3191 mL
50 mM	0.0464 mL	0.2319 mL	0.4638 mL

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