Description：

PFI-2 is a potent, selective, and cell-active lysine methyltransferase SETD7 inhibitor with K_{i (app)} and IC50 of 0.33 nM and 2 nM, 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.

Chemical Information：

Molecular Weight (MW)		535.98
Formula		C23H25F4N3O3S.HCl
CAS No.		1627607-87-7
Solubility (25°C) *	DMSO	99 mg/mL (184.7 mM)
	Water	4 mg/mL warmed (7.46 mM)
	Alcohol	25 mg/mL warmed (46.64 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8657 mL	9.3287 mL	18.6574 mL
5 mM	0.3731 mL	1.8657 mL	3.7315 mL
10 mM	0.1866 mL	0.9329 mL	1.8657 mL
50 mM	0.0373 mL	0.1866 mL	0.3731 mL

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