Description：

PF-562271 is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM in cell-free assays, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs.

Chemical Information：

Molecular Weight (MW)		507.49
Formula		C21H20F3N7O3S
CAS No.		717907-75-0
Solubility (25°C) *	DMSO	100 mg/mL warmed (197.04 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9705 mL	9.8524 mL	19.7048 mL
5 mM	0.3941 mL	1.9705 mL	3.9410 mL
10 mM	0.1970 mL	0.9852 mL	1.9705 mL
50 mM	0.0394 mL	0.1970 mL	0.3941 mL

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