Description：

PF-04929113 (SNX-5422) is a potent and selective HSP90 inhibitor with K_d of 41 nM and induces Her-2 degradation with IC50 of 37 nM. Phase 1/2.

Chemical Information：

Molecular Weight (MW)		521.53
Formula		C25H30F3N5O4
CAS No.		908115-27-5
Solubility (25°C) *	DMSO	104 mg/mL (199.41 mM)
	Water	Insoluble
	Alcohol	5 mg/mL (9.58 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9174 mL	9.5872 mL	19.1744 mL
5 mM	0.3835 mL	1.9174 mL	3.8349 mL
10 mM	0.1917 mL	0.9587 mL	1.9174 mL
50 mM	0.0383 mL	0.1917 mL	0.3835 mL

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