Description：

Pexidartinib (PLX3397) is an oral, potent mutil-targeted receptor tyrosine kinase inhibitor of CSF-1R, Kit, and Flt3 with IC50 of 20 nM, 10 nM and 160 nM, respectively. Phase 3.

Chemical Information：

Molecular Weight (MW)		417.81
Formula		C20H15ClF3N5
CAS No.		1029044-16-3
Solubility (25°C) *	DMSO	83 mg/mL (198.65 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.3934 mL	11.9672 mL	23.9343 mL
5 mM	0.4787 mL	2.3934 mL	4.7869 mL
10 mM	0.2393 mL	1.1967 mL	2.3934 mL
50 mM	0.0479 mL	0.2393 mL	0.4787 mL

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