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AS1842856

AS1842856

Catalog Number: CC8378 Rank: comment rank 5

Size Price Qty
$ 102.00
$ 347.00
Total:
    
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Description:

AS1842856 is a cell-permeable inhibitor that blocks the transcription activity of Foxo1 with IC50 of 33 nM. It could directly bind to the active Foxo1, but not the Ser256-phosphorylated form.

Chemical Information:

Molecular Weight (MW) 347.38
Formula

 

C18H22FN3O3

 

CAS No. 836620-48-5
Solubility (25°C) * DMSO 23 mg/mL (66.2 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
PDK1
12 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.8787 mL 14.3935 mL 28.7869 mL
5 mM 0.5757 mL 2.8787 mL 5.7574 mL
10 mM 0.2879 mL 1.4393 mL 2.8787 mL
50 mM 0.0576 mL 0.2879 mL 0.5757 mL


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