Description：

ORY-1001 (RG-6016) 2HCl is an orally active and selective lysine-specific demethylase LSD1/KDM1A inhibitor with IC50 of <20 nM, with high selectivity against related FAD dependent aminoxidases. Phase 1.

Chemical Information：

Molecular Weight (MW)		303.27
Formula		C15H22N2 . 2HCl
CAS No.		1431326-61-2
Solubility (25°C) *	DMSO	5 mg/mL (16.48 mM)
	Water	61 mg/mL (201.14 mM)
	Alcohol	4 mg/mL warmed (13.18 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.2974 mL	16.4870 mL	32.9739 mL
5 mM	0.6595 mL	3.2974 mL	6.5948 mL
10 mM	0.3297 mL	1.6487 mL	3.2974 mL
50 mM	0.0659 mL	0.3297 mL	0.6595 mL

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