Description：

Nutlin-3b is a p53/MDM2 antagonist or inhibitor with IC50 value of 13.6 μM, 150-fold less potent (+)-enantiomer of Nutlin-3 as in comparison with opposite (-)-enantiomer Nutlin-3a.

Chemical Information：

Molecular Weight (MW)		581.49
Formula		C30H30Cl2N4O4
CAS No.		675576-97-3
Solubility (25°C) *	DMSO	100 mg/mL (171.97 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (171.97 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7197 mL	8.5986 mL	17.1972 mL
5 mM	0.3439 mL	1.7197 mL	3.4394 mL
10 mM	0.1720 mL	0.8599 mL	1.7197 mL
50 mM	0.0344 mL	0.1720 mL	0.3439 mL

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