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NMS-P937 (NMS1286937)

NMS-P937 (NMS1286937)

Catalog Number: CC7411 Rank: comment rank 5

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$ 102.00
$ 347.00
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Description:

NMS-P937 (NMS1286937) is an orally available, selective Polo-like Kinase 1 (PLK1) inhibitor with IC50 of 2 nM, 5000-fold selectivity over PLK2/PLK3. Phase 1.

Chemical Information:

Molecular Weight (MW) 532.52
Formula

 

C24H27F3N8O3

 

CAS No. 1034616-18-6
Solubility (25°C) * DMSO 42 mg/mL warmed (78.87 mM)
Water Insoluble
Alcohol 10 mg/mL warmed (18.77 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8779 mL 9.3893 mL 18.7786 mL
5 mM 0.3756 mL 1.8779 mL 3.7557 mL
10 mM 0.1878 mL 0.9389 mL 1.8779 mL
50 mM 0.0376 mL 0.1878 mL 0.3756 mL


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