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Nintedanib (BIBF 1120)

Nintedanib (BIBF 1120)

Catalog Number: CC1166 Rank: comment rank 5

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Description:

Nintedanib (BIBF 1120) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM in cell-free assays. Phase 3.

Chemical Information:

Molecular Weight (MW) 539.62
Formula

 

C31H33N5O4

 

CAS No. 656247-17-5
Solubility (25°C) * DMSO 6 mg/mL (11.11 mM)
Water Insoluble
Alcohol 3 mg/mL (5.55 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.8532 mL 9.2658 mL 18.5316 mL
5 mM 0.3706 mL 1.8532 mL 3.7063 mL
10 mM 0.1853 mL 0.9266 mL 1.8532 mL
50 mM 0.0371 mL 0.1853 mL 0.3706 mL


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