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Niclosamide

Niclosamide

Catalog Number: CC3186 Rank: comment rank 5

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Description:

Niclosamide can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5).

Chemical Information:

Molecular Weight (MW) 327.12
Formula

 

C13H8Cl2N2O4

 

CAS No. 50-65-7
Solubility (25°C) * DMSO Insoluble
Water Insoluble
Alcohol


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.0570 mL 15.2849 mL 30.5698 mL
5 mM 0.6114 mL 3.0570 mL 6.1140 mL
10 mM 0.3057 mL 1.5285 mL 3.0570 mL
50 mM 0.0611 mL 0.3057 mL 0.6114 mL


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