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MK-8776 (SCH 900776)

MK-8776 (SCH 900776)

Catalog Number: CC2891 Rank: comment rank 5

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Description:

MK-8776 (SCH 900776) is a selective Chk1 inhibitor with IC50 of 3 nM in a cell-free assay. It shows 500-fold selectivity against Chk2. Phase 2.

Chemical Information:

Molecular Weight (MW) 376.25
Formula

 

C15H18BrN7

 

CAS No. 891494-63-6
Solubility (25°C) * DMSO 3 mg/mL (7.97 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.6578 mL 13.2890 mL 26.5781 mL
5 mM 0.5316 mL 2.6578 mL 5.3156 mL
10 mM 0.2658 mL 1.3289 mL 2.6578 mL
50 mM 0.0532 mL 0.2658 mL 0.5316 mL


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