Description：

A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

Chemical Information：

Molecular Weight (MW)		342.61
Formula		C13H10Cl3N5
CAS No.		899431-18-6
Solubility (25°C) *	DMSO	61 mg/mL (178.04 mM)
	Water	61 mg/mL (178.04 mM)
	Alcohol	20 mg/mL warmed (58.37 mM)

Biological Activity：

Targets IC50

ErbB2 EGFR 9.0 nM 1.5 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9188 mL	14.5939 mL	29.1877 mL
5 mM	0.5838 mL	2.9188 mL	5.8375 mL
10 mM	0.2919 mL	1.4594 mL	2.9188 mL
50 mM	0.0584 mL	0.2919 mL	0.5838 mL

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