Description：

LY411575 is a potent γ-secretase inhibitor with IC50 of 0.078 nM/0.082 nM (membrane/cell-based), also inhibits Notch cleavage with IC50 of 0.39 nM in APP or NΔE expressing HEK293 cells.

Chemical Information：

Molecular Weight (MW)		479.48
Formula		C26H23F2N3O4
CAS No.		209984-57-6
Solubility (25°C) *	DMSO	95 mg/mL (198.13 mM)
	Water	Insoluble
	Alcohol	13 mg/mL (27.11 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.0856 mL	10.4280 mL	20.8559 mL
5 mM	0.4171 mL	2.0856 mL	4.1712 mL
10 mM	0.2086 mL	1.0428 mL	2.0856 mL
50 mM	0.0417 mL	0.2086 mL	0.4171 mL

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