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LY2090314

LY2090314

Catalog Number: CC7219 Rank: comment rank 5

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Description:

LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases.

Chemical Information:

Molecular Weight (MW) 512.53
Formula

 

C28H25FN6O3

 

CAS No. 603288-22-8
Solubility (25°C) * DMSO 100 mg/mL (195.11 mM)
Water Insoluble
Alcohol 2 mg/mL warmed (3.9 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.9511 mL 9.7555 mL 19.5111 mL
5 mM 0.3902 mL 1.9511 mL 3.9022 mL
10 mM 0.1951 mL 0.9756 mL 1.9511 mL
50 mM 0.0390 mL 0.1951 mL 0.3902 mL


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