Description：

Larotrectinib (LOXO-101) sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).

Chemical Information：

Molecular Weight (MW)		526.51
Formula		C21H22F2N6O2.H2O4S
CAS No.		1223405-08-0
Solubility (25°C) *	DMSO	100 mg/mL (189.92 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (189.92 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8993 mL	9.4965 mL	18.9930 mL
5 mM	0.3799 mL	1.8993 mL	3.7986 mL
10 mM	0.1899 mL	0.9496 mL	1.8993 mL
50 mM	0.0380 mL	0.1899 mL	0.3799 mL

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