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KPT-276

KPT-276

Catalog Number: CC7407 Rank: comment rank 5

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$ 189.00
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Description:

KPT-276 is an orally bioavailable selective CRM1 inhibitor.

Chemical Information:

Molecular Weight (MW) 426.26
Formula

 

C16H10F8N4O

 

CAS No. 1421919-75-6
Solubility (25°C) * DMSO 20 mg/mL (46.91 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
CDK9 CDK1 CDK4
20 nM 79 nM 63 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.3460 mL 11.7299 mL 23.4599 mL
5 mM 0.4692 mL 2.3460 mL 4.6920 mL
10 mM 0.2346 mL 1.1730 mL 2.3460 mL
50 mM 0.0469 mL 0.2346 mL 0.4692 mL


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