Description：

KN-93 Phosphate is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with K_i of 0.37 μM, no remarkable inhibitory effects on APK, PKC, MLCK or Ca2+-PDE activities.

Chemical Information：

Molecular Weight (MW)		599.03
Formula		C26 H29 Cl N2 O4 S . H3 O4 P
CAS No.		1188890-41-6
Solubility (25°C) *	DMSO	100 mg/mL (166.93 mM)
	Water	92 mg/mL (153.58 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

Endothelin B Endothelin A 391 nM 0.5 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.6694 mL	8.3468 mL	16.6937 mL
5 mM	0.3339 mL	1.6694 mL	3.3387 mL
10 mM	0.1669 mL	0.8347 mL	1.6694 mL
50 mM	0.0334 mL	0.1669 mL	0.3339 mL

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