Description：

Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with K_i of 0.34 μM, 6.5 μM and 0.93 μM in RH7777 cell lines, respectively, shows no activity at LPA4, LPA5, LPA6.

Chemical Information：

Molecular Weight (MW)		474.96
Formula		C23H23ClN2O5S
CAS No.		355025-24-0
Solubility (25°C) *	DMSO	94 mg/mL (197.91 mM)
	Water	Insoluble
	Alcohol	94 mg/mL (197.91 mM)

Biological Activity：

Targets IC50

Dynamin1/2 ~15 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.1054 mL	10.5272 mL	21.0544 mL
5 mM	0.4211 mL	2.1054 mL	4.2109 mL
10 mM	0.2105 mL	1.0527 mL	2.1054 mL
50 mM	0.0421 mL	0.2105 mL	0.4211 mL

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