Description：

JIB-04 is a pan-selective Jumonji histone demethylase inhibitor with IC50 of 230, 340, 855, 445, 435, 1100, and 290 nM for JARID1A, JMJD2E, JMJD3, JMJD2A, JMJD2B, JMJD2C, and JMJD2D in cell-free assays, respectively.

Chemical Information：

Molecular Weight (MW)		308.76
Formula		C17H13ClN4
CAS No.		199596-05-9
Solubility (25°C) *	DMSO	25 mg/mL warmed (80.96 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

PPARδ 1 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.2388 mL	16.1938 mL	32.3876 mL
5 mM	0.6478 mL	3.2388 mL	6.4775 mL
10 mM	0.3239 mL	1.6194 mL	3.2388 mL
50 mM	0.0648 mL	0.3239 mL	0.6478 mL

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