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IPA-3

IPA-3

Catalog Number: CC7249 Rank: comment rank 5

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Description:

IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).

Chemical Information:

Molecular Weight (MW) 350.45
Formula

 

C20H14O2S2

 

CAS No. 42521-82-4
Solubility (25°C) * DMSO 70 mg/mL (199.74 mM)
Water Insoluble
Alcohol 7 mg/mL (19.97 mM)


Biological Activity:

Targets
IC50
JMJD2A JMJD2E JMJD2B JMJD3 JARID1A JMJD2D
445 nM 340 nM 435 nM 855 nM 230 nM 290 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.8535 mL 14.2674 mL 28.5347 mL
5 mM 0.5707 mL 2.8535 mL 5.7069 mL
10 mM 0.2853 mL 1.4267 mL 2.8535 mL
50 mM 0.0571 mL 0.2853 mL 0.5707 mL


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