Description：

IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases.

Chemical Information：

Molecular Weight (MW)		189.17
Formula		C10H7NO3
CAS No.		5852-78-8
Solubility (25°C) *	DMSO	37 mg/mL (195.59 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

DNMT3A DNMT1 DNMT3B 8 μM 6 μM 7.5 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	5.2863 mL	26.4313 mL	52.8625 mL
5 mM	1.0573 mL	5.2863 mL	10.5725 mL
10 mM	0.5286 mL	2.6431 mL	5.2863 mL
50 mM	0.1057 mL	0.5286 mL	1.0573 mL

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