Description：

IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NF-κB pathway.

Chemical Information：

Molecular Weight (MW)		383.67
Formula		C15H8ClF6NO2
CAS No.		978-62-1
Solubility (25°C) *	DMSO	10 mg/mL (26.06 mM)
	Water	Insoluble
	Alcohol	77 mg/mL (200.69 mM)

Biological Activity：

Targets IC50

mutant EGFR < 20 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.6064 mL	13.0320 mL	26.0641 mL
5 mM	0.5213 mL	2.6064 mL	5.2128 mL
10 mM	0.2606 mL	1.3032 mL	2.6064 mL
50 mM	0.0521 mL	0.2606 mL	0.5213 mL

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