Description：

IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.

Chemical Information：

Molecular Weight (MW)		412.25
Formula		C16H30N2.2HBr
CAS No.		162831-31-4
Solubility (25°C) *	DMSO	82 mg/mL (198.9 mM)
	Water	82 mg/mL (198.9 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

R132H-IDH1 R132C-IDH1 0.07 μM 0.16 μM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.4257 mL	12.1286 mL	24.2571 mL
5 mM	0.4851 mL	2.4257 mL	4.8514 mL
10 mM	0.2426 mL	1.2129 mL	2.4257 mL
50 mM	0.0485 mL	0.2426 mL	0.4851 mL

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