Description：

Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.

Chemical Information：

Molecular Weight (MW)		516.65
Formula		C29H32N4O3S
CAS No.		422513-13-1
Solubility (25°C) *	DMSO	103 mg/mL (199.36 mM)
	Water	Insoluble
	Alcohol	Insoluble

Biological Activity：

Targets IC50

DOT1L 0.3 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.9355 mL	9.6777 mL	19.3555 mL
5 mM	0.3871 mL	1.9355 mL	3.8711 mL
10 mM	0.1936 mL	0.9678 mL	1.9355 mL
50 mM	0.0387 mL	0.1936 mL	0.3871 mL

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