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4-Hydroxytamoxifen

4-Hydroxytamoxifen

Catalog Number: CC7983 Rank: comment rank 5

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Description:

4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.

Chemical Information:

Molecular Weight (MW) 387.51
Formula

 

C26H29NO2

 

CAS No. 68392-35-8
Solubility (25°C) * DMSO 77 mg/mL (198.7 mM)
Water Insoluble
Alcohol Insoluble


Biological Activity:

Targets
IC50
EGFR
0.70 nM


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5806 mL 12.9029 mL 25.8058 mL
5 mM 0.5161 mL 2.5806 mL 5.1612 mL
10 mM 0.2581 mL 1.2903 mL 2.5806 mL
50 mM 0.0516 mL 0.2581 mL 0.5161 mL


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