Description：

GW4869 is a neutral, noncompetitive inhibitor of sphingomyelinase (SMase) with an IC50 of 1 μM. It is selective for N-SMase, and does not inhibit acid SMase at up to at least 150 μM.

Chemical Information：

Molecular Weight (MW)		577.5
Formula		C30H28N6O2.2HCl.XH2O
CAS No.		6823-69-4
Solubility (25°C) *	DMSO	1 mg/mL warmed (1.73 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.7316 mL	8.6580 mL	17.3160 mL
5 mM	0.3463 mL	1.7316 mL	3.4632 mL
10 mM	0.1732 mL	0.8658 mL	1.7316 mL
50 mM	0.0346 mL	0.1732 mL	0.3463 mL

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