Description：

GNF-7 is a potent type-II kinase Bcr-Abl inhibitor with IC50 of <5 nM, 61 nM, 122 nM, 136 nM, and 133 nM for M351T, T315I, E255 V, G250E, and c-Abl, respectively.

Chemical Information：

Molecular Weight (MW)		547.53
Formula		C28H24F3N7O2
CAS No.		839706-07-9
Solubility (25°C) *	DMSO	20 mg/mL (36.52 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8264 mL	9.1319 mL	18.2638 mL
5 mM	0.3653 mL	1.8264 mL	3.6528 mL
10 mM	0.1826 mL	0.9132 mL	1.8264 mL
50 mM	0.0365 mL	0.1826 mL	0.3653 mL

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