Description：

GNF-5837 is a selective, and orally bioavailable pan-TRK inhibitor for TrkA, and TrkB with IC50 of 8 nM, and 12 nM, respectively.

Chemical Information：

Molecular Weight (MW)		535.49
Formula		C28H21F4N5O2
CAS No.		1033769-28-6
Solubility (25°C) *	DMSO	100 mg/mL (186.74 mM)
	Water	Insoluble
	Alcohol	9 mg/mLwarmed (16.8 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.8674 mL	9.3372 mL	18.6745 mL
5 mM	0.3735 mL	1.8674 mL	3.7349 mL
10 mM	0.1867 mL	0.9337 mL	1.8674 mL
50 mM	0.0373 mL	0.1867 mL	0.3735 mL

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