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GKT137831

GKT137831

Catalog Number: CC7327 Rank: comment rank 5

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$ 333.00
$ 697.00
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Description:

GKT137831 is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectivelyl; ~10-fold selectivity towards NOX1, 4 and 5 over NOX2, does not inhibit XO or scavange ROS/RNS.

Chemical Information:

Molecular Weight (MW) 394.85
Formula

 

C21H19ClN4O2

 

CAS No. 1218942-37-0
Solubility (25°C) * DMSO 78 mg/mL warmed (197.54 mM)
Water Insoluble
Alcohol Insoluble


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 2.5326 mL 12.6630 mL 25.3261 mL
5 mM 0.5065 mL 2.5326 mL 5.0652 mL
10 mM 0.2533 mL 1.2663 mL 2.5326 mL
50 mM 0.0507 mL 0.2533 mL 0.5065 mL


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