Description：

AMD3465 is a monomacrocyclic CXCR4 antagonist.

Chemical Information：

Molecular Weight (MW)		896.07
Formula		C24H38N6.6HBr
CAS No.		185991-07-5, 185991-24-6 (free b
Solubility (25°C) *	DMSO	2 mg/mL (2.23 mM)
	Water	98 mg/mL (109.36 mM)
	Alcohol	Insoluble

Biological Activity：

Targets IC50

F508del-CFTR G551D-CFTR 25 nM 100 nM

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.1160 mL	5.5799 mL	11.1598 mL
5 mM	0.2232 mL	1.1160 mL	2.2320 mL
10 mM	0.1116 mL	0.5580 mL	1.1160 mL
50 mM	0.0223 mL	0.1116 mL	0.2232 mL

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