Description：

Gambogic Acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-X_L, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.

Chemical Information：

Molecular Weight (MW)		628.75
Formula		C38H44O8
CAS No.		2752-65-0
Solubility (25°C) *	DMSO	100 mg/mL (159.04 mM)
	Water	Insoluble
	Alcohol	100 mg/mL (159.04 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	1.5905 mL	7.9523 mL	15.9046 mL
5 mM	0.3181 mL	1.5905 mL	3.1809 mL
10 mM	0.1590 mL	0.7952 mL	1.5905 mL
50 mM	0.0318 mL	0.1590 mL	0.3181 mL

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