Description：

10074-G5 is a c-Myc inhibitor that binds to and distorts the bHLH-ZIP domain of c-Myc (Kd = 2.8 µM), thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (IC50 = 146 µM).

Chemical Information：

Molecular Weight (MW)		332.31
Formula		C18H12N4O3
CAS No.		413611-93-5
Solubility (25°C) *	DMSO	60 mg/mL (180.55 mM)
	Water	Insoluble
	Alcohol	10 mg/mL warmed (30.09 mM)

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	3.0092 mL	15.0462 mL	30.0924 mL
5 mM	0.6018 mL	3.0092 mL	6.0185 mL
10 mM	0.3009 mL	1.5046 mL	3.0092 mL
50 mM	0.0602 mL	0.3009 mL	0.6018 mL

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