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FRAX597

FRAX597

Catalog Number: CC7427 Rank: comment rank 5

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Description:

FRAX597 is a potent, ATP-competitive inhibitor of group I PAKs with IC50 of 8 nM, 13 nM, and 19 nM for PAK1, PAK2, and PAK3, respectively.

Chemical Information:

Molecular Weight (MW) 558.10
Formula

 

C29H28ClN7OS

 

CAS No. 1286739-19-2
Solubility (25°C) * DMSO 14 mg/mL warmed (25.08 mM)
Water Insoluble
Alcohol 1 mg/mL (1.79 mM)


Preparing Stock Solutions

Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 1.7918 mL 8.9590 mL 17.9179 mL
5 mM 0.3584 mL 1.7918 mL 3.5836 mL
10 mM 0.1792 mL 0.8959 mL 1.7918 mL
50 mM 0.0358 mL 0.1792 mL 0.3584 mL


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