Description：

ETC-1002,also known as Bempedoic acid, is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C and to avoid side effects associated with existing LDL-C lowering therapies.ETC-1002 is an activator of hepatic AMP-activated protein kinase (AMPK). It has potent inhibitory activity against hepatic ATP-citrate lyase(IC50=29 uM).

Chemical Information：

Molecular Weight (MW)		344.49
Formula		C19H36O5
CAS No.		738606-46-7
Solubility (25°C) *	DMSO	68 mg/mL (197.39 mM)
	Water	Insoluble
	Alcohol	Insoluble

Preparing Stock Solutions

Concentration Volume (DMSO) Mass	1 mg	5 mg	10 mg
1 mM	2.9028 mL	14.5142 mL	29.0284 mL
5 mM	0.5806 mL	2.9028 mL	5.8057 mL
10 mM	0.2903 mL	1.4514 mL	2.9028 mL
50 mM	0.0581 mL	0.2903 mL	0.5806 mL

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